Journal article
The effect of ordered and partially ordered surface topography on bone cell responses: A review
N Gui, W Xu, DE Myers, R Shukla, HP Tang, M Qian
Biomaterials Science | ROYAL SOC CHEMISTRY | Published : 2018
DOI: 10.1039/c7bm01016h
Abstract
Implant surfaces play important roles in regulating protein adsorption and determining subsequent cell responses, including cell attachment, proliferation, migration and differentiation. With rapid developments in micro- and nano-fabrication methods and additive manufacturing (3D printing) technologies, precisely controlled patterns such as partially ordered or ordered patterns can now be generated on bone implant surfaces, rather than restricted to randomly roughened surfaces. Over the last two decades, much effort has been dedicated to manipulating cell responses through surface topographical modifications. This review discusses the recent developments and understanding of surface topograp..
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Awarded by Australian Research Council
Funding Acknowledgements
Na Gui acknowledges the support from the China Scholarship Council (CSC) for a CSC PhD scholarship and also the support from RMIT University for a tuition fee waiver scholarship. In addition, the authors wish to thank Dr Serena Duchi and Dr Carmine Onofrillo (University of Melbourne/St Vincent's Hospital Melbourne) for useful discussion. This work was supported by the Australian Research Council (ARC) through ARC LP140100607, Xi'an Sailong Metal Materials Co., Ltd, China, and Anatomics Pty Ltd, Australia. H. P. Tang and M. Qian further acknowledges the support from the National Natural Science Foundation of China through Grant 51528401.